（脂蛋白受体）参考文献

1．刘秉文.脂类代谢Ⅱ：磷脂、胆固醇及血浆脂蛋白代谢.见顾天爵主编，生物化学.北京：人民卫生出版社，1995

2．冯宗忱，低密度脂蛋白受体家族及清道夫受体，见：王克勤主编，脂蛋白与动脉粥样硬化，北京：人民卫生出版社，1995：278-317

3．Hobbs H H,Brown M S,Goldstein JL.et alDeletion of exon encoding cystein-rich repeat of LDL receptor alters itsbinding specificityin subject with familial hypercholesterolemia.J BiolChem,1986,261l:13114-13120

4.BrownM S,Godlstein J L.Binding & degradaion of low dernsity ,lipoproteins bycultred human fibroblasts;Comparision of cells from a normal subject and from apatient with homozygous familial hypercholesterolemiaJ.Biol.Chem,1974,249:5153-5162

5.YamamotoT,Davis C G,Brown M S,et al.The human LDl receptor:A cystein-rich proein withmultiple Alusequences in its mRNa .Cell,1984,39:27-38

6.BrownM S,Goldstein J L.A receptor-mediated pathway for cholesterolhomeostasis.Science,1986,232:34-47

7.MulerC.Xanthomata,hypercholesterolemia,angina pectoris Acta Med Scod ,1938,89(suppl):75-84

8.YamamotoT.Bishop R W,Brown M S,et al.Deletion in cystein rich region of LDL receptorimpdees transport to cell sruface in WHHL rabbit .Science,1986,232:1230-1237

9.RussellD W,Lehrman M A,Sudhof T C.et al ,The LDL receptor in familialhypercholesterolemia:Use of human mutations to dissect a membrane protein .ColdSpring Harbor Symp Quant Biol.1987,51:811-819

10.GoldsteinJ L,Brown M S.Reguation fo the mevalonate pathoay .Nature,1990,343:425-430

11.ChenW-J,Goldstein JL.Brown M S.NPXY,a sequence often fornd in cytoplasmic tails ,isrequred for coated pit-mediated internalization of the low density lipoproteinreceptor J Biol Chem,1990,265:3116-3123

12.EsserV,Limbird L E,Brown M S,et al.Mutational analysis of ligand binding domain ofthe low density lipoprotein receptor.Jbiol Chem.1988,263:13282-13290

13.RussdllD W,Brown M,Coldstein J L.Different combinations of cystein rich receptor totwo different proteins.J.Biol.Chem,1989,264:21682-21688

14.WatanabeY.Serial inbreeding of rabbits with herediataryhyapelipidemia(WHHL-rabbit),Incidence and development of atheroclerodis&xanthoma .Atherosclerosis.1980,36:261-268

15.DavisC G,Goldstein JL,Sudhof T D,et al Growth factor homology region in LDL receptormediates acid-dependent dissociation and receptor recyclingNatre,1987,326:760-765

16.Davis C G,elhammer A,Russell D W,et al.D W,et al.Deletion of clustercd O-lindedcarbohydrates does not impair runction of low density lipoprotein receptor intransfected fibroblasts.J Biol Chem,1986,261:2828-2838

17.KodamaT,Freeman M,Rohrer L,et al . Type I macrophage scavenger receptor contains a-helical and collagenlike coiled coils .Nature,1990,343:531-535

18.RohrerL,Freeman M,Kodama T,et al .Coiled-coil fibrors domains mediate ligand bindingby macrophage scavenger receptor typeⅡ.Nature,1990,343:570-571

19.DoiT,Higashino K,Kurihara Y,et al.Charged collagen structure mediates therecognition of negatively charged macromolecules by macrophage scavengerreceptors.J Biol Chem,1993,268:2126-2133

20.YokodeM,Pathak R K,Hammer R E,et al .Cytoplasmic seqrence required fof basolateraltargeting of LDL receptor in livers of transgenic mice .J Cell Biol,1992,117:39046

21.Brown M S ,Goldstein J Lipoprotein metabolism in the macrophage :Implicationsfor cholesterol deposition in atherosclerosis .Annu Rev Biochem,1983,52:223-261

22.TakahashiS,Kawarabayasi Y,Nakai T,et al .Rabbit very low density lipoprtein receptor;Alow density lipoprotein receptor-like protein with distinct ligand specificity.Proc Natl Acad Sci USA ,1992,89:9252-9256

23.Kita ,T Nagano Y,Yokode M,et al Probucol prevents the progression ofatherosclerosis in Watanabe heritable hyperlipidemic rabbit ,an animal modelfor familial hypercholesterolemia.Proc Natl Acad Sci USA,1987,84:5928-5931

24.Kita T,Brown M,Sbilheimer D W,et al .Delayed clearance of very low density andintemediate density lipoproteins with enhanced conversion to low densitylipprotein in WHHL rabbits Proc Natl Acad Sci USA,1982,79:5963-5997

25.Van Lenten B J,Fogelman A M,Jacdson R L,et al.Receptor-mediated uptade ofremnant lipoproteins by cholesterol-loaded human monocyte-macrophages .J BiolChem,1985,260:8783-8788

26.WillnowT,Goldstein J,Orth K,et al Low density lipoprotein receptor related protein andgp330 bind similar ligands including plasminogen activator-inhibitor complexesand lactoferrin,an inhibitor of chylomicron remnant clearance.J BiolChem,1992,267:2172-26180

27.InabaT,Gotoda T,Shimano H,et al. Platelet-derived growth factor induced c-fms andscavenger receptor genes in vascular smooth cells J BioChem,1992,267:1307-13112

28.Resnicd D,et al The srcR superamily .Trends Biochem Sci,1994,19:5

29.酒井寿郎，山本德男.LDL,VLDL,

30.?阡?信羲,小宫山一雄,清水健一郎,他.LDl Recepter-related Proteinの?}硬化巢の发现I.